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December is Leukemia & Lymphoma Awareness Month

 Leukemia is the general name for four different types of blood cancers. The ways that individuals with leukemia are affected and treated and the rate at which the disease progresses, are different with each type of leukemia.

Lymphoma is a general term for a group of cancers that originate in the lymphatic system. The lymphomas are divided into two major categories: Hodgkin lymphoma and all other lymphomas, called non-Hodgkin lymphomas.

Leukemia & Lymphoma Awareness Month

 The prefix "lymph-" indicates their origin in the malignant change of a lymphocyte and the suffix "-oma" is derived from the Greek suffix denoting "tumor." About 53 percent of the blood cancers that occur each year are lymphomas.

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Signs and symptoms of Leukemia and Lymphoma are similar to those of other ailments, but eventually may become more persistent and severe. See your physician if any of the following signs and symptoms persist or recur.

Leukemia - Signs and Symptoms may include:

  • Pale complexion
  • Weakness
  • Chronic fatigue
  • Shortness of breath
  • Unexplained fever
  • Bruising easily
  • Exaggerated bleeding after injuries
  • Recurrent infection
  • Pain in joints and bones
  • Increased size of lymph nodes, liver or spleen

Lymphoma - Signs and Symptoms may include:

  • Painless swelling of lymph nodes: neck, armpits, groin or other areas
  • Fever
  • Night sweats
  • Tiredness
  • Weight loss
  • Itchy skin
  • Skin rash

What You Should Know

Leukemia – Facts: Leukemia is a disease of the marrow, the spongy center of bones that makes blood cells. In leukemia the body makes too many abnormal white cells.

The major forms of leukemia are divided into four categories. Myelogenous and Lymphocytic leukemia each have acute and chronic forms. The terms myelogenous or lyphocytic denote the cell type involved.

Leukemia may occur in two forms: Acute leukemia and Chronic leukemia.

Acute leukemia is a rapidly progressing disease that affects mostly cells that are unformed or nor yet fully developed or differentiated. These immature cells cannot carry out their normal functions.

Chronic leukemia progresses slowly and permits the growth of greater numbers of more developed cells. In general, these more mature cells can carry out some of their normal functions.

Thus, the four major types of leukemia are:

  • Acute Myelogenous Leukemia
  • Acute Lymphocytic Leukemia
  • Chronic Myelogenous Leukemia
  • Chronic Lymphocytic Leukemia

The ability to measure specific features of cells has led to further subclassification of the major categories of leukemia. The categories and subsets allow the physician to decide what treatment works best for the cell type and how quickly the disease may develop.

Chronic lyphocytic leukemia occurs most often in adults, but can occur at any age. It accounts for approximately one-half of leukemia cases.

Lymphoma – Facts:

Lymphoma is a type of cancer that develops in the lymphatic system, or collections of lymphatic tissue, in organs like the stomach or intestines.

Lymphomas may involve the marrow and the blood in some cases or may spread from one site to other parts of the body.

Lymphocytic leukemias originate and are most prominent in the marrow and spill over into the blood. They occasionally spread to involve the lymph nodes.

There are two main types of lymphoma: Hodgkin's lymphoma and non-Hodgkin’s lymphoma.

Hodgkin's lymphoma generally spreads from one group of lymph nodes to the next in an orderly way. It is often seen in adolescents or young adults who have a better chance of recovery than those with other kinds of lymphoma.

Non-Hodgkin’s lymphoma generally spreads through the lymphatic system in a less orderly way than Hodgkin’s lymphoma. It is usually seen in adults who can have a good chance of recovery depending on factors such as how advanced the disease is.

There are more than 30 different types of non-Hodgkin’s lymphomas. Nearly 90% of these are B-cell lymphomas. There are 14 different types of B-cell lymphomas.

Diffuse large B-cell lymphoma, (a fast growing lymphoma) and follicular lymphoma (a slow-growing lymphoma) are the two most common B-cell lymphomas. Together these two types make up more than half of all non-Hodgkin’s lymphomas.

Other types of non-Hodgkin’s lymphomas are T-cell, NK cell lymphomas, and Immunodeficiency-associated lymphoproliferative disorders.

People infected with human T-cell lymphocytotropic virus (HTLV) or human immunodeficiency virus (HIV) also have an increased probability of developing Hodgkin’s lymphoma.

There is an increase in the incidence of non-Hodgkin’s lymphomas in farming communities. Studies point out specific ingredients in herbicides and pesticides being associated with lymphoma. However, the number of lymphoma cases caused by such exposures has not been determined.

Acquired Immune Deficiency Syndrome (AIDS) is caused by the human immunodeficiency virus (HIV), which attacks and weakens the body's immune system. The immune system is then unable to fight infection and diseases that invade the body. People with HIV disease have an increased risk of developing infections, lymphoma and other types of cancer.

Epstein-Barr virus infection may play a role in the increased risk of non-Hodgkin’s lymphomas in persons with immune suppression as a result of organ transplantation and its therapy. People with transplanted organs are treated with drugs that suppress their immune system to keep it from attacking the new organs. This process creates a risk of developing non-Hodgkin’s lymphomas. The exact risk depends on which drugs are used and the doses involved. Infection with the hepatitis C virus may be a risk factor for non-Hodgkin’s lymphoma.

What You Can Do

At this time, there are no special tests to find Leukemia or Lymphoma early. The best course of action to take is to pay attention to any possible signs or symptoms of this disease and report them to your doctor right away.

Close observation is important for children:

  1. With a known genetic abnormality that might increase their risk of leukemia.
  2. Who have had another cancer treated with chemotherapy, or combined chemotherapy and radiation therapy.
  3. Who have received organ transplants and are taking immune system-suppressing drugs. Acquired Immune Deficiency Syndrome (AIDS) is mostly spread among adults through sex or the sharing of dirty needles by IV drug users. Treating AIDS with new drugs seems to reduce the risk of developing non-Hodgkin’s lymphoma.
For more information, visit Leukemia & Lymphoma Society
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